Changes in cell-mediated immunity in kidney transplant recipients with active CMV infection

CMV Infection in CMV-Seropositive Kidney Transplant Recipients

Cytomegalovirus (CMV) infection is a major cause of morbidity in kidney transplant recipients. CMV seropositivity is common in the general population, with a reported prevalence ranging from 30 to 97% (Paya, 2001; Preiksaitis et al., 2005). After primary infection, CMV establishes life-long latency. During the past 2 decades, major advances in the management of CMV infection of transplant patie...

Covid-19 infection in kidney transplant recipients: a case report

Antibody mediated acute rejection in kidney transplant recipients with CMV infection.

CMV infection of transplant recipients.

C YTOMEGALOVIRUS (CMV) LlSUdly CiXlSeS ZiSyIllptOmatic or clinically insignificant infection in the immunocompetent host. Thereafter, the virus persists in a latent state, but may be reactivated by immunosuppression. Reactivation of latent infection most commonly occurs in the context of Human Immunodeficiency Virus (HIV) infection and allogeneic organ transplantation, but has also been describ...

Cytomegalovirus (CMV) immune monitoring with ELISPOT and QuantiFERON-CMV assay in seropositive kidney transplant recipients

Although cytomegalovirus (CMV) specific cell-mediated immunity (CMI) has been suggested as a predictive marker for CMV infection, proper CMI monitoring strategy in CMV-seropositive recipients and optimal method are not defined. The aim of this study was to evaluate two interferon gamma release assays during early post-transplant period as a predictor of the development of CMV infection in CMV-s...